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1

Synthesis of 2-Substituted Piperazines via Direct α-Lithiation.

Martin Berkheij, Lisan van der Sluis, Claudia Sewing, Dennis J. den Boer, Jan Willem Terpstra, Henk Hiemstra, Wouter I. Iwema Bakker, Adri van den Hoogenband, Jan H. van Haarseveen

Journal:

Year:

2005

File:

PDF, 24 KB

2005

2

Piperazinyl oxime ethers as NK-1 receptor antagonists

Adri van den Hoogenband, Jan H. van Maarseveen, Andrew C. McCreary, Arie T. Mulder, Guus J.M. van Scharrenburg, Herman H. van Stuivenberg, Theo J.J. Zethof, Barbara Zijta, Wouter I. Iwema Bakker

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 125 KB

english, 2006

3

Synthesis of 2-substituted piperazines via direct α-lithiation

Martin Berkheij, Lisan van der Sluis, Claudia Sewing, Dennis J. den Boer, Jan Willem Terpstra, Henk Hiemstra, Wouter I. Iwema Bakker, Adri van den Hoogenband, Jan H. van Maarseveen

Journal:

Tetrahedron Letters

Year:

2005

Language:

english

File:

PDF, 115 KB

english, 2005

4

An efficient one-pot synthesis of novel 4-aryl-1-methyloxindoles

Adri van den Hoogenband, Jos H.M. Lange, Wouter I. Iwema-Bakker, Jack A.J. den Hartog, Jord van Schaik, Rolf W. Feenstra, Jan Willem Terpstra

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 104 KB

english, 2006

5

The Suzuki-Miyaura cross coupling reactions on solid support. Link to solution phase directed ortho metalation. The Leznoff acetal linker approach to biaryl and heterobiaryl aldehydes

S. Chamoin, S. Houldsworth, C.G. Kruse, W. Iwema Bakker, V. Snieckus

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 169 KB

english, 1998

6

N ′-(Arylsulfonyl)pyrazoline-1-carboxamidines as Novel, Neutral 5-Hydroxytryptamine 6 Receptor (5-HT 6 R) Antagonists with Unique Structural Features

van Loevezijn, Arnold, Venhorst, Jennifer, Iwema Bakker, Wouter I., de Korte, Cor G., de Looff, Wouter, Verhoog, Stefan, van Wees, Jan-Willem, van Hoeve, Martijn, van de Woestijne, Rob P., van der Neu

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 3.72 MB

english, 2011

7

Design and Synthesis of a Maximally Diverse and Druglike Screening Library Using REM Resin Methodology

Barn, D., Caulfield, W., Cowley, P., Dickins, R., Bakker, W. Iwema, McGuire, R., Morphy, J. Richard, Rankovic, Z., Thorn, M.

Journal:

Journal of Combinatorial Chemistry

Year:

2001

Language:

english

File:

PDF, 389 KB

english, 2001

8

Encyclopedia of Reagents for Organic Synthesis || Lithium Diisopropylamide

Iwema Bakker, Wouter I.

Year:

2001

Language:

english

File:

PDF, 1.13 MB

english, 2001

9

Kinetically stable complexes of alkali cations with calixspherands: an evaluation of shielding

Iwema Bakker, Wouter I., Haas, Marijke, Khoo-Beattie, Corinne, Ostaszewski, Ryszard, Franken, Sybille M., den Hertog, Herman J., Verboom, Willem, de Zeeuw, Dick, Harkema, Sybolt, Reinhoudt, David N.

Journal:

Journal of the American Chemical Society

Year:

1994

Language:

english

File:

PDF, 1.39 MB

english, 1994

10

Kinetically stable silver complexes of calixspherands

Bakker, Wouter I. Iwema, Verboom, Willem, Reinhoudt, David N.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1994

Language:

english

File:

PDF, 197 KB

english, 1994

11

A conformational study of the calixspherand and its complexes with alkalimetal cations

Groenen, Leo C., Brunink, Jos A. J., Bakker, Wouter I. Iwema, Harkema, Sybolt, Wijmenga, Sybren S., Reinhoudt, David N.

Journal:

Journal of the Chemical Society Perkin Transactions 2

Year:

1992

Language:

english

File:

PDF, 883 KB

english, 1992

12

A general method for the determination of the kinetic stability of macrocyclic alkali-metal complexes with rates of decomplexation below 10?3 s?1

Bakker, Wouter I. Iwema, Haas, Marijke, den Hertog, Herman J., Verboom, Willem, de Zeeuw, Dick, Reinhoudt, David N.

Journal:

Journal of the Chemical Society Perkin Transactions 2

Year:

1994

Language:

english

File:

PDF, 552 KB

english, 1994

13

Optimization of N’-(arylsulfonyl)pyrazoline-1-carboxamidines by exploiting a novel interaction site in the 5-HT6 antagonistic binding pocket

Loevezijn, Arnold van, Venhorst, Jennifer, Iwema Bakker, Wouter I., Lange, Jos H.M., Looff, Wouter de, Henzen, Remco, Vries, Jelle de, van de Woestijne, Rob P., den Hartog, Arnold P., Verhoog, Stefan,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 618 KB

english, 2016

14

Encyclopedia of Reagents for Organic Synthesis || Lithium Diisopropylamide

Iwema Bakker, Wouter I.

Year:

2001

Language:

english

File:

PDF, 925 KB

english, 2001

15

Calixarenes, chemical chameleons

van Dienst, E., Bakker, W. I. Iwema, Engbersen, J. F. J., Verboom, W., Reinhoudt, D. N.

Journal:

Pure & Applied Chemistry

Year:

1993

Language:

english

File:

PDF, 275 KB

english, 1993